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Analysis have shown that the rotor induced
centrifugal forces move the entire product bed creating a
denser film deposition. i.e. To obtain a wurster identical
drug release profile, one would have to apply a little less
coating agent with the rotor.
Our Rotor is not limited to film coating only, but permits
a number of processing options. Rotor granulation can be accomplished
by spraying a suitable binder suspension on powders. Both
granulate production and spher'oidization is completed by
the spherical rope motion of the formulation. The final stage
drying can be rapidly achieved as the large free area around
the rotor disc allows the throughput of large air volumes.
Pellet ization, such as the production of non-pareils, is
accomplished by rapid powder and binder addition onto dummy
seals through a single, combined bottom spray nozzle (in this
case tangential spray). This process allows weight gain of
approximately 250% per hour.
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