Fipronil is a broad spectrum insecticide that disrupts the insect central nervous system by blocking the passage of chloride ions through the GABA receptor and glutamate-gated chloride (GluCl) channels, components of the central nervous system. This causes hyperexcitation of contaminated insects' nerves and muscles.
Specificity of fipronil on insects may come from a better efficacy on GABA receptor, but also on because GluCl channels do not exist in mammals.
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| Fipronil Granules - WDG (IUPAC) Name | Fipronil Granules - WDG Identifiers | Fipronil Granules - WDG data | ||||||||||||||||||||
| (RS)-5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl)-1H-pyrazole-3-carbonitrile |
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