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Clothianidin Granules - WDG
Clothianidin Granules - WDG
Clothianidin is an insecticide developed by Takeda Chemical Industries and Bayer AG. Similar to thiamethoxam and imidacloprid, it is a neonicotinoid. Neonicotinoids are a class of insecticides which act on the central nervous system of insects with lower toxicity to mammals.

According to theEnvironmental Protection Agency, "the fate and disposition of clothianidin in the environment suggest a compound that is a systemic insecticide that is persistent and mobile, stable to hydrolysis, and has potential to leach to ground water, as well as runoff to surface waters."

Neonicotinoid insecticides are among the most widely used insecticides worldwide, but recently the uses of some members of this class have been restricted in some countries due to a possible connection to honey bee colony collapse disorder.

Clothianidin was first given conditional registration for use as a pesticide by the United States Environmental Protection Agency in April of 2003, pending the completion of additional study of its safety to be done by December of 2004 (later extended to May of 2005).

The study was not completed until August of 2007. Clothianidin was granted an unconditional registration for use as a seed treatment for corn and canola on April 22, 2010.

However, on November 2, 2010, after a review of the studies supplied by the manufacturer, the EPA released a memorandum in which they stated that the Bayer field study submitted did not appear to be adequate and it was reclassified as "supplemental".


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Clothianidin Granules - WDG
(IUPAC) Name
Clothianidin Granules - WDG Identifiers Clothianidin Granules - WDG data
1-(2-Chlor-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine
CAS number : 210880-92-5 (E)
PubChem : 213027 (E)
ChemSpider : 184723 (E)
KEGG : C18508
MeSH : Clothianidin
ChEBI : CHEBI:39178
ChEMBL : CHEMBL259727
Formula : C6H8ClN5O2S
Mol. mass : 249.68 g mol−1
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